职称/职务

副教授/系支部书记（兼副主任）

研究方向

主要研究方向为生物与医药：

1、药物新剂型与制剂创制技术

2、新型纳米前药设计与纳米诊疗体系构建

3、制药分离工程

邮箱

chinaytx@ahut.edu.cn

学习工作经历

2024-至今 安徽工业大学，新葡的京集团35222vip，副教授

2016-2024 安徽工业大学，新葡的京集团35222vip，讲师

2013-2016 中国药科大学，制药工程学专业，博士

2010-2013 中国药科大学，生物化工专业，硕士

2006-2010 江南大学，生物工程专业，学士

主要科研项目及成果

主持国家重点研发计划任务等国家级、省部级以上课题4项，发表SCI、EI论文30余篇，授权国家发明专利十余项。主要从事化学生物学与制药工程相关专业教学与科研，安徽省工信厅生物医药领域高新项目评审专家，中国医药工业杂志等期刊青年编委，承担International Journal of Pharmaceutics, Food Research International, Current Opinion in Food Science, Microchemical Journal, Journal of Molecular Structure、中国医药工业杂志等多个SCI、EI期刊审稿人。累计指导学生参加全国大学生制药工程设计竞赛获得全国二等奖4项、三等奖6项，国际互联网+大学生创新大赛（中国国际大学生创新大赛）国家级金奖1项、银奖1项，省级金奖3项、铜奖1项，全国医药院校药学/中药学专业大学生实验技能展示活动三等奖1项，校级教学成果奖3项。

热忱欢迎具有化学化工、材料、生物医药及相关交叉学科背景的研究生、本科生加入研究团队。课题组与国内双一流高校等研究机构保持密切合作关系，可推荐或联合培养方式到相关课题组继续深造。欢迎有意向的同学与我们联系, Email: chinaytx@ahut.edu.cn。

近期承担科研项目：

1、国家重点研发计划政府间国际科技创新合作重点专项任务（2023YFE0110100），2023.10-2026.10，主持。

2、安徽省教育厅重点研究项目（2023AH051127），2023.7-2025.7，主持。

3、安徽省自然科学基金（2108085QB85），2021.1-2022.12，主持。

4、产学研项目（RH2300000567），2023.5-2025.5，主持

近期第一或通讯作者发表SCI、EI论文:

[1] Tingxuan Yan* et al., Fabrication of Nanoflower Like Dual ligand Copper Metal-Organic Framework using solvothermal method to Enhance the Antibacterial Activity of Baicalin and Tedizolid Phosphate, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2026, 731, 139054. （主要完成学生：丁强、张林潇等）

[2] Tingxuan Yan* et al., Inner Filter Effect-Induced Fluorescence Quenching via Nanoflower like Probe for Highly Sensitive Detection of 3-Nitrotyrosine Biomarkers in Human Serum, Microchemical Journal, 2026,116421. https://doi.org/10.1016/j.microc.2025.116421 （主要完成学生：高梦婷、苏嘉豪等）

[3] Tingxuan Yan* et al., Vo-AgFeO₂−x nanozymes treat infected wounds and promote wound healing, Nano Research, 2025, 19, 94907899.

[4] Tingxuan Yan* et al., Efficient extraction of Polygonum hydropiper L. Polyphenol using Dual-ligand Cu MOF and bioactive activity study of Polyphenol-MOF complex microparticles, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2025, DOI: 10.1007/s10847-025-01317-w.（主要完成学生：高梦婷、张林潇等）

[5] Tingxuan Yan* et al., Tumor microenvironment-responsive diagnosis and treatment of integrated drug-loaded CdTe quantum dots for treatment tumors, Nanotechnology, 2025, 36, 235101. （主要完成学生：苏嘉豪等）

[6] Tingxuan Yan* et al., Self-Supply of Hydrogen Peroxide by a Bimetal-Based Nanocatalytic Platform to Enhance Chemodynamic Therapy for Tumor Treatment, Nanotechnology, 2025, 36, 045101. （主要完成学生：苏嘉豪等）

[7] Tingxuan Yan* et al., Natural flavonoid glycoside-based self-assembled nanoparticles for synergistic antibacterial activity and improved antioxidant properties, Journal of Drug Delivery Science and Technology, 2025, 105, 106583.

[8] Tingxuan Yan* et al., Deep-eutectic solvent coated paper: A reusable multi-purpose device for rapid visualization, adulteration identification, efficient removal and recycling of dyes in both food and environmental samples, Microchemical Journal, 2025, 209, 112625.

[9] Tingxuan Yan* et al., Preparation of indapamide-HP-β-CD and indapamide-PVP nanoparticles by supercritical antisolvent technology: Experimental and DPD simulations, The Journal of Supercritical Fluids, 2024, 209, 106262.

[10] Tingxuan Yan* et al., Fabrication of betamethasone micro- and nanoparticles using supercritical antisolvent technology: In vitro drug release study and Caco-2 cell cytotoxicity evaluation, European Journal of Pharmaceutical Sciences, 2023, 181, 106341.

[11] Tingxuan Yan* et al., Fabrication of hesperetin/hydroxypropyl-β-cyclodextrin complex nanoparticles for enhancement of bioactivity using supercritical antisolvent technology, Journal of Molecular Structure, 2023, 1279, 134947.

[12] Tingxuan Yan* et al., Fabrication of apigenin nanoparticles using antisolvent crystallization technology: A comparison of supercritical antisolvent, ultrasonic-assisted liquid antisolvent, and high-pressure homogenization technologies, International Journal of Pharmaceutics, 2022, 624, 121981.

[13] Tingxuan Yan* et al., Filter paper-based colorimetric analysis: An instrument-free strategy for semiquantitative naked-eye detection of food colorants, Food Chemistry, 2022, 390, 133087.  

[14] Tingxuan Yan* et al., Molecularly imprinted upconversion nanoparticles for active tumor targeting and microinvasive photothermal therapy, Journal of Materials Science, 2022, 57, 5177-5197.

[15] Tingxuan Yan* et al., Preparation, characterization and evaluation of the antioxidant capacity and antitumor activity of myricetin microparticles formated by supercritical antisolvent technology, The Journal of Supercritical Fluids, 2021, 175, 105290.  

[16] Tingxuan Yan* et al., Preparation and characterization of baicalein/ hydroxypropyl-β-cyclodextrin inclusion complex for enhancement of solubility, antioxidant activity and antibacterial activity using supercritical antisolvent technology, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2020, 96, 285–295.

[17] Tingxuan Yan* et al., Preparation of irbesartan composite microparticles by supercritical aerosol solvent extraction system for dissolution enhancement, The Journal of Supercritical Fluids, 2019, 153, 104594.

近期第一发明人专利

[1] 颜庭轩 等，一种超临界压缩流体沉淀法制备雷公藤红素纳米颗粒的方法, ZL201810082477.7  专利授权
[2] 颜庭轩 等，吗啡啉类酸性离子液体在超临界压缩流体沉淀法制备黄芩素微胶囊中的应用, ZL201710455554.4专利授权
[3] 颜庭轩 等，一种黑枸杞中总黄酮、提取方法、应用, ZL201911288532.9专利授权
[4] 颜庭轩 等，一种超声协同高压均质技术制备芹菜素超细颗粒的方法, ZL202111239933.2  专利授权
[5] 颜庭轩 等，一种枇杷叶提取物纳米胶囊、制备方法及应用, 2019-12-12, 中国, ZL201911274027.9  专利授权

[6] 颜庭轩 等，一种硼酸功能化CdTe量子点及肿瘤靶向诊疗一体化复合纳米药物, ZL202311122035.8专利授权

[7] 颜庭轩 等，自供给过氧化氢的双金属基纳米凝胶及其制备方法和应用，CN202311280719.0，专利公开

[8] 颜庭轩 等，HPLC法检测L-谷氨酸中异构体杂质的装置及方法，

CN202410492821.5，专利公开